Anti-Epidermal Growth Factor Receptor Gene Therapy for Glioblastoma

Glioblastoma multiforme (GBM) is the most common and aggressive primary intracranial brain tumor in adults with a mean survival of 14 to 15 months. Aberrant activation of the epidermal growth factor receptor (EGFR) plays a significant role in GBM progression, with amplification or overexpression of...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hicks, Martin J., Chiuchiolo, Maria J., Ballon, Douglas, Dyke, Jonathan P., Aronowitz, Eric, Funato, Kosuke, Tabar, Viviane, Havlicek, David, Fan, Fan, Sondhi, Dolan, Kaminsky, Stephen M., Crystal, Ronald G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053413/
https://ncbi.nlm.nih.gov/pubmed/27711187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162978
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