Damaged DNA-binding protein down-regulates epigenetic mark H3K56Ac through histone deacetylase 1 and 2

Acetylated histone H3 lysine 56 (H3K56Ac) is one of the reversible histone post-translational modifications (PTMs) responsive to DNA damage. We previously described a biphasic decrease and increase of epigenetic mark H3K56Ac in response to ultraviolet radiation (UVR)-induced DNA damage. Here, we rep...

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Bibliografiske detaljer
Udgivet i:Mutat Res
Main Authors: Zhu, Qianzheng, Battu, Aruna, Ray, Alo, Wani, Gulzar, Qian, Jiang, He, Jinshan, Wang, Qi-en, Wani, Altaf A.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053336/
https://ncbi.nlm.nih.gov/pubmed/26255936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2015.01.005
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