Filaggrin failure – from ichthyosis vulgaris to atopic eczema and beyond

The main proteinaceous component of the keratohyalin granules within the granular layer keratinocytes of the epidermis is the giant, repetitive polyprotein profilaggrin. When granular layer cells commit to terminal differentiation to form the flattened squames of the stratum corneum, profilaggrin is...

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Библиографические подробности
Опубликовано в: :Br J Dermatol
Главный автор: McLean, W.H.I.
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2016
Предметы:
British Skin Foundation, Skin Deep ‐ 20 Years of Research, 20th Anniversary Conference, 13th October 2016, Royal College of Physicians, London, U.K. Publication of this supplement was supported by Stiefel, a GSK company
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053269/
https://ncbi.nlm.nih.gov/pubmed/27667308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjd.14997
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