Subtyping sub-Saharan esophageal squamous cell carcinoma by comprehensive molecular analysis

Esophageal squamous cell carcinoma (ESCC) is endemic in regions of sub-Saharan Africa (SSA), where it is the third most common cancer. Here, we describe whole-exome tumor/normal sequencing and RNA transcriptomic analysis of 59 patients with ESCC in Malawi. We observed similar genetic aberrations as...

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Udgivet i:JCI Insight
Main Authors: Liu, Wenjin, Snell, Jeff M., Jeck, William R., Hoadley, Katherine A., Wilkerson, Matthew D., Parker, Joel S., Patel, Nirali, Mlombe, Yohannie B., Mulima, Gift, Liomba, N. George, Wolf, Lindsey L., Shores, Carol G., Gopal, Satish, Sharpless, Norman E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053149/
https://ncbi.nlm.nih.gov/pubmed/27734031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.88755
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