Nalaganje...
CGG-repeat dynamics and FMR1 gene silencing in fragile X syndrome stem cells and stem cell-derived neurons
BACKGROUND: Fragile X syndrome (FXS), a common cause of intellectual disability and autism, results from the expansion of a CGG-repeat tract in the 5′ untranslated region of the FMR1 gene to >200 repeats. Such expanded alleles, known as full mutation (FM) alleles, are epigenetically silenced in d...
Shranjeno v:
| izdano v: | Mol Autism |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2016
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5053128/ https://ncbi.nlm.nih.gov/pubmed/27713816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13229-016-0105-9 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|