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Soluble Adenylyl Cyclase Is Required for Retinal Ganglion Cell and Photoreceptor Differentiation

PURPOSE: We have previously demonstrated that soluble adenylyl cyclase (sAC) is necessary for retinal ganglion cell (RGC) survival and axon growth. Here, we further investigate the role of sAC in neuronal differentiation during retinal development. METHODS: Chx10 or Math5 promoter-driven Cre-Lox rec...

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Publicado en:Invest Ophthalmol Vis Sci
Autores principales: Shaw, Peter X., Fang, Jiahua, Sang, Alan, Wang, Yan, Kapiloff, Michael S., Goldberg, Jeffrey L.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Association for Research in Vision and Ophthalmology 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053116/
https://ncbi.nlm.nih.gov/pubmed/27679853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-19465
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