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Soluble Adenylyl Cyclase Is Required for Retinal Ganglion Cell and Photoreceptor Differentiation

PURPOSE: We have previously demonstrated that soluble adenylyl cyclase (sAC) is necessary for retinal ganglion cell (RGC) survival and axon growth. Here, we further investigate the role of sAC in neuronal differentiation during retinal development. METHODS: Chx10 or Math5 promoter-driven Cre-Lox rec...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Shaw, Peter X., Fang, Jiahua, Sang, Alan, Wang, Yan, Kapiloff, Michael S., Goldberg, Jeffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053116/
https://ncbi.nlm.nih.gov/pubmed/27679853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-19465
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