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Composite sequential Monte Carlo test for post-market vaccine safety surveillance

Group sequential hypothesis testing is now widely used to analyze prospective data. If Monte Carlo simulation is used to construct the signaling threshold, the challenge is how to manage the type I error probability for each one of the multiple tests without losing control on the overall significanc...

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Detalles Bibliográficos
Publicado en:Stat Med
Autor Principal: Silva, Ivair R.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5052811/
https://ncbi.nlm.nih.gov/pubmed/26561330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6805
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