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Activation and increase of radio-sensitive CD11b+ recruited Kupffer cells/macrophages in diet-induced steatohepatitis in FGF5 deficient mice

We have recently reported that Kupffer cells consist of two subsets, radio-resistant resident CD68+ Kupffer cells and radio-sensitive recruited CD11b+ Kupffer cells/macrophages (Mφs). Non-alcoholic steatohepatitis (NASH) is characterized not only by hepatic steatosis but also chronic inflammation an...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Nakashima, Hiroyuki, Nakashima, Masahiro, Kinoshita, Manabu, Ikarashi, Masami, Miyazaki, Hiromi, Hanaka, Hiromi, Imaki, Junko, Seki, Shuhji
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5052649/
https://ncbi.nlm.nih.gov/pubmed/27708340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34466
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