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Suppression of the CD8 T cell response by human papillomavirus type 16 E7 occurs in Langerhans cell-depleted mice

Human papillomavirus (HPV) is an epitheliotropic virus that is the primary causal agent for cervical cancer. Langerhans cells (LC) are skin antigen presenting cells that are reduced in number in HPV-infected skin. The aim of this study was to understand the immune-modulatory effects of HPV16 E7 on L...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jemon, K., Leong, C.-M., Ly, K., Young, S. L., McLellan, A. D., Hibma, M. H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5052534/
https://ncbi.nlm.nih.gov/pubmed/27708419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34789
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