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Reversal of Human Papillomavirus-Specific T Cell Immune Suppression through TLR Agonist Treatment of Langerhans Cells Exposed to Human Papillomavirus Type 16

Human papillomavirus (HPV) type 16 infects the epithelial layer of cervical mucosa and is causally associated with the generation of cervical cancer. Langerhans cells (LC) are the resident antigen-presenting cells at the site of infection and therefore are responsible for initiating an immune respon...

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Main Authors: Fahey, Laura M., Raff, Adam B., Da Silva, Diane M., Kast, W. Martin
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745289/
https://ncbi.nlm.nih.gov/pubmed/19234187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803645
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