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Large-Scale Conformational Transitions in Supercoiled DNA Revealed by Coarse-Grained Simulation
Topological constraints, such as those associated with DNA supercoiling, play an integral role in genomic regulation and organization in living systems. However, physical understanding of the principles that underlie DNA organization at biologically relevant length scales remains a formidable challe...
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| Publicat a: | Biophys J |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Biophysical Society
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5052444/ https://ncbi.nlm.nih.gov/pubmed/27705758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.07.045 |
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