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Coarse-Grain Simulations Reveal Movement of the Synaptobrevin C-Terminus in Response to Piconewton Forces

Fusion of neurosecretory vesicles with the plasma membrane is mediated by SNARE proteins, which transfer a force to the membranes. However, the mechanism by which this force transfer induces fusion pore formation is still unknown. The neuronal vesicular SNARE protein synaptobrevin 2 (syb2) is anchor...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Lindau, Manfred, Hall, Benjamin A., Chetwynd, Alan, Beckstein, Oliver, Sansom, Mark S.P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Biophysical Society 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433613/
https://ncbi.nlm.nih.gov/pubmed/23009845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.08.007
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