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Coarse-Graining Provides Insights on the Essential Nature of Heterogeneity in Actin Filaments

Experiments have shown that actin is structurally polymorphic, but knowledge of the details of molecular level heterogeneity in both the dynamics of a single subunit and the interactions between subunits is still lacking. Here, using atomistic molecular dynamics simulations of the actin filament, we...

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Détails bibliographiques
Auteurs principaux: Fan, Jun, Saunders, Marissa G., Voth, Gregory A.
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446683/
https://ncbi.nlm.nih.gov/pubmed/22995506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.08.029
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