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Cause and consequences of the activated type I interferon system in SLE
Patients with systemic lupus erythematosus (SLE) have an increased expression of type I interferon (IFN)-regulated genes (an IFN signature), which is caused by an ongoing production of type I IFNs by plasmacytoid dendritic cells (pDCs). The reasons behind the continuous IFN production in SLE are the...
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| Udgivet i: | J Mol Med (Berl) |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer Berlin Heidelberg
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5052287/ https://ncbi.nlm.nih.gov/pubmed/27094810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-016-1421-4 |
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