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Gene discovery by chemical mutagenesis and whole-genome sequencing in Dictyostelium
Whole-genome sequencing is a useful approach for identification of chemical-induced lesions, but previous applications involved tedious genetic mapping to pinpoint the causative mutations. We propose that saturation mutagenesis under low mutagenic loads, followed by whole-genome sequencing, should a...
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| 發表在: | Genome Res |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5052037/ https://ncbi.nlm.nih.gov/pubmed/27307293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.205682.116 |
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