SUMOylation of Rad52-Rad59 synergistically change the outcome of mitotic recombination

Homologous recombination (HR) is essential for maintenance of genome stability through double-strand break (DSB) repair, but at the same time HR can lead to loss of heterozygosity and uncontrolled recombination can be genotoxic. The post-translational modification by SUMO (small ubiquitin-like modif...

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Veröffentlicht in:DNA Repair (Amst)
Hauptverfasser: Silva, Sonia, Altmannova, Veronika, Eckert-Boulet, Nadine, Kolesar, Peter, Gallina, Irene, Hang, Lisa, Chung, Inn, Arneric, Milica, Zhao, Xiaolan, Buron, Line Due, Mortensen, Uffe H., Krejci, Lumir, Lisby, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5051639/
https://ncbi.nlm.nih.gov/pubmed/27130983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2016.04.001
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