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Using EHR-Linked Biobank Data to Study Metformin Pharmacogenomics

Metformin is a commonly prescribed diabetes medication whose mechanism of action is poorly understood. In this study we utilized EHR-linked biobank data to elucidate the impact of genomic variation on glycemic response to metformin. Our study found significant gene- and SNP-level associations within...

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Detalhes bibliográficos
Publicado no:Stud Health Technol Inform
Main Authors: Breitenstein, Matthew K., Simon, Gyorgy, Ryu, Euijung, Armasu, Sebastian M., Weinshilboum, Richard M., Wang, Liewei, Pathak, Jyotishman
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5051541/
https://ncbi.nlm.nih.gov/pubmed/25991289
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