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Leveraging an Electronic Health Record-Linked Biorepository to Generate a Metformin Pharmacogenomics Hypothesis

Metformin is a first-line antihyperglycemic agent commonly prescribed in type 2 diabetes mellitus (T2DM), but whose pharmacogenomics are not clearly understood. Further, due to accumulating evidence highlighting the potential for metformin in cancer prevention and treatment efforts it is imperative...

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Veröffentlicht in:AMIA Jt Summits Transl Sci Proc
Hauptverfasser: Breitenstein, Matthew K., Wang, Liewei, Simon, Gyorgy, Ryu, Euijung, Armasu, Sebastian M., Ray, Balmiki, Weinshilboum, Richard M., Pathak, Jyotishman
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Medical Informatics Association 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525256/
https://ncbi.nlm.nih.gov/pubmed/26306225
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