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Olive Oil-derived Oleocanthal as Potent Inhibitor of Mammalian Target of Rapamycin: Biological Evaluation and Molecular Modeling Studies

The established anticancer and neuroprotective properties of oleocanthal combined with the reported role of mammalian target of rapamycin (mTOR) in cancer and Alzheimer’s disease development encouraged us to examine the possibility that oleocanthal inhibits mTOR. To validate this hypothesis, we dock...

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Detalhes bibliográficos
Publicado no:Phytother Res
Main Authors: Khanfar, Mohammad A., Bardaweel, Sanaa K., Akl, Mohamed R., El Sayed, Khalid A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5051273/
https://ncbi.nlm.nih.gov/pubmed/26248874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ptr.5434
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