Llwytho...
Pulmonary Hypertension in the Newborn GTP-Cyclohydrolase 1-Deficient Mouse
Tetrahydrobiopterin (BH4) is a regulator of endothelial nitric oxide synthase (eNOS) activity. Deficient levels result in eNOS uncoupling with a shift from nitric oxide (NO) to superoxide generation. The hph-1 mutant mouse has deficient GTP-cyclohydrolase 1 (GTPCH1) activity resulting in low BH4 tis...
Wedi'i Gadw mewn:
Cyhoeddwyd yn: | Free Radic Biol Med |
---|---|
Prif Awduron: | , , , , , |
Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
2011
|
Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5050525/ https://ncbi.nlm.nih.gov/pubmed/21982896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.09.012 |
Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|