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Necrostatin-1 treatment inhibits osteocyte necroptosis and trabecular deterioration in ovariectomized rats
Estrogen (E2) deficiency has been associated with accelerated osteocyte apoptosis. Our previous study showed necroptosis accelerated the loss of osteocytes in E2 deficiency-induced osteoporosis in rats in addition to apoptosis, but the mechanism involved remains. Necroptosis is a caspase-independent...
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| Vydáno v: | Sci Rep |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5050438/ https://ncbi.nlm.nih.gov/pubmed/27703177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33803 |
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