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Necrostatin-1 and necroptosis inhibition: Pathophysiology and therapeutic implications

Necrostatin-1 (Nec-1) is a RIP1-targeted inhibitor of necroptosis, a form of programmed cell death discovered and investigated in recent years. There are already many studies demonstrating the essential role of necroptosis in various diseases, including inflammatory diseases, cardiovascular diseases...

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Bibliografische gegevens
Gepubliceerd in:Pharmacol Res
Hoofdauteurs: Cao, Liyuan, Mu, Wei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier Ltd. 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962892/
https://ncbi.nlm.nih.gov/pubmed/33181319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2020.105297
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