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A Tetravalent Sub-unit Dengue Vaccine Formulated with Ionizable Cationic Lipid Nanoparticle induces Significant Immune Responses in Rodents and Non-Human Primates

Dengue virus has emerged as an important arboviral infection worldwide. As a complex pathogen, with four distinct serotypes, the development of a successful Dengue virus vaccine has proven to be challenging. Here, we describe a novel Dengue vaccine candidate that contains truncated, recombinant, Den...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Swaminathan, Gokul, Thoryk, Elizabeth A., Cox, Kara S., Smith, Jeffrey S., Wolf, Jayanthi J., Gindy, Marian E., Casimiro, Danilo R., Bett, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050434/
https://ncbi.nlm.nih.gov/pubmed/27703172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34215
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