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Smad4 controls bone homeostasis through regulation of osteoblast/osteocyte viability
Regulation of osteoblast and osteocyte viability is essential for bone homeostasis. Smad4, a major transducer of bone morphogenetic protein and transforming growth factor-β signaling pathways, regulates apoptosis in various cell types through a mitochondrial pathway. However, it remains poorly under...
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| Veröffentlicht in: | Exp Mol Med |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5050296/ https://ncbi.nlm.nih.gov/pubmed/27585718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2016.75 |
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