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Zebrafish small molecule screens: Taking the phenotypic plunge

Target based chemical screens are a mainstay of modern drug discovery, but the effectiveness of this reductionist approach is being questioned in light of declines in pharmaceutical R & D efficiency. In recent years, phenotypic screens have gained increasing acceptance as a complementary/alterna...

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Bibliografiske detaljer
Udgivet i:Comput Struct Biotechnol J
Main Authors: Williams, Charles H., Hong, Charles C.
Format: Artigo
Sprog:Inglês
Udgivet: Research Network of Computational and Structural Biotechnology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050293/
https://ncbi.nlm.nih.gov/pubmed/27721960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2016.09.001
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