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A variable active site residue influences the kinetics of response regulator phosphorylation and dephosphorylation

Two-component regulatory systems, minimally composed of a sensor kinase and a response regulator protein, are common mediators of signal transduction in microorganisms. All response regulators contain a receiver domain with conserved active site residues that catalyze the signal activating and deact...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Immormino, Robert M., Silversmith, Ruth E., Bourret, Robert B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050157/
https://ncbi.nlm.nih.gov/pubmed/27589219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00645
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