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Probing Mechanistic Similarities Between Response Regulator Signaling Proteins and HAD Phosphatases

Response regulator signaling proteins and phosphatases of the haloacid dehalogenase (HAD) superfamily share strikingly similar folds, active site geometries, and reaction chemistry. Proteins from both families catalyze the transfer of a phosphoryl group from a substrate to one of their own aspartyl...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Immormino, Robert M., Starbird, Chrystal, Silversmith, Ruth E., Bourret, Robert B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516285/
https://ncbi.nlm.nih.gov/pubmed/25928369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00286
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