CCL2 produced by the glioma microenvironment is essential for the recruitment of regulatory T cells and myeloid-derived suppressor cells

In many aggressive cancers, such as glioblastoma multiforme (GBM), progression is enabled by local immunosuppression driven by the accumulation of regulatory T cells (Treg) and myeloid-derived suppressor cells (MDSC). However, the mechanistic details of how Treg and MDSC are recruited in various tum...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Chang, Alan L., Miska, Jason, Wainwright, Derek A., Dey, Mahua, Rivetta, Claudia V., Yu, Dou, Kanojia, Deepak, Pituch, Katarzyna C., Qiao, Jian, Pytel, Peter, Han, Yu, Wu, Meijing, Zhang, Lingjiao, Horbinski, Craig M., Ahmed, Atique U., Lesniak, Maciej S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050119/
https://ncbi.nlm.nih.gov/pubmed/27530322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-0144
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