ImmunoPET for assessing the differential uptake of a CD146-specific monoclonal antibody in lung cancer

PURPOSE: Overexpression of CD146 in solid tumors has been linked to disease progression, invasion, and metastasis. In this study, we describe the generation of a (64)Cu-labeled CD146-specific antibody for quantitative immunoPET imaging of CD146 expression in six lung cancer models. METHODS: The anti...

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Udgivet i:Eur J Nucl Med Mol Imaging
Main Authors: Sun, Haiyan, England, Christopher G., Hernandez, Reinier, Graves, Stephen A., Majewski, Rebecca L., Kamkaew, Anyanee, Jiang, Dawei, Barnhart, Todd E., Yang, Yunan, Cai, Weibo
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050101/
https://ncbi.nlm.nih.gov/pubmed/27342417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-016-3442-1
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