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ImmunoPET imaging of CD146 expression in malignant brain tumors

Recently, the overexpression of CD146 and its potential as a therapeutic target in high-grade gliomas, the most lethal type of brain cancer, was uncovered. In this study, we describe the generation of (89)Zr-Df-YY146, a novel (89)Zr-labeled monoclonal antibody (mAb) for the targeting and quantificat...

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Publicat a:Mol Pharm
Autors principals: Hernandez, Reinier, Sun, Haiyan, England, Christopher G., Valdovinos, Hector F., Barnhart, Todd E., Yang, Yunan, Cai, Weibo
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935599/
https://ncbi.nlm.nih.gov/pubmed/27280694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.6b00372
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