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Evidence for an age-dependent decline in axon regeneration in the adult mammalian central nervous system

How aging impacts axon regeneration after central nervous system (CNS) injury is not known. We assessed the impact of age on axon regeneration induced by Pten deletion in corticospinal and rubrospinal neurons, two neuronal populations with distinct innate regenerative abilities. As in young mice, Pt...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Geoffroy, Cédric G., Hilton, Brett J., Tetzlaff, Wolfram, Zheng, Binhai
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050004/
https://ncbi.nlm.nih.gov/pubmed/27050519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.03.028
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