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Evidence for an age-dependent decline in axon regeneration in the adult mammalian central nervous system

How aging impacts axon regeneration after central nervous system (CNS) injury is not known. We assessed the impact of age on axon regeneration induced by Pten deletion in corticospinal and rubrospinal neurons, two neuronal populations with distinct innate regenerative abilities. As in young mice, Pt...

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Publicado en:Cell Rep
Autores principales: Geoffroy, Cédric G., Hilton, Brett J., Tetzlaff, Wolfram, Zheng, Binhai
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050004/
https://ncbi.nlm.nih.gov/pubmed/27050519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.03.028
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