Chargement en cours...
Sequence amplification via cell passaging creates spurious signals of positive adaptation in influenza virus H3N2 hemagglutinin
Clinical influenza A virus isolates are frequently not sequenced directly. Instead, a majority of these isolates (∼70% in 2015) are first subjected to passaging for amplification, most commonly in non-human cell culture. Here, we find that this passaging leaves distinct signals of adaptation, which...
Enregistré dans:
| Publié dans: | Virus Evol |
|---|---|
| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2016
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5049878/ https://ncbi.nlm.nih.gov/pubmed/27713835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ve/vew026 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|