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Whole Genome Sequence Analysis of a Large Isoniazid-Resistant Tuberculosis Outbreak in London: A Retrospective Observational Study

BACKGROUND: A large isoniazid-resistant tuberculosis outbreak centred on London, United Kingdom, has been ongoing since 1995. The aim of this study was to investigate the power and value of whole genome sequencing (WGS) to resolve the transmission network compared to current molecular strain typing...

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Vydáno v:PLoS Med
Hlavní autoři: Casali, Nicola, Broda, Agnieszka, Harris, Simon R., Parkhill, Julian, Brown, Timothy, Drobniewski, Francis
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5049847/
https://ncbi.nlm.nih.gov/pubmed/27701423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002137
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