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Whole Genome Sequence Analysis of a Large Isoniazid-Resistant Tuberculosis Outbreak in London: A Retrospective Observational Study

BACKGROUND: A large isoniazid-resistant tuberculosis outbreak centred on London, United Kingdom, has been ongoing since 1995. The aim of this study was to investigate the power and value of whole genome sequencing (WGS) to resolve the transmission network compared to current molecular strain typing...

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Detalhes bibliográficos
Publicado no:PLoS Med
Main Authors: Casali, Nicola, Broda, Agnieszka, Harris, Simon R., Parkhill, Julian, Brown, Timothy, Drobniewski, Francis
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5049847/
https://ncbi.nlm.nih.gov/pubmed/27701423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002137
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