A Crimean-Congo hemorrhagic fever (CCHF) viral vaccine expressing nucleoprotein is immunogenic but fails to confer protection against lethal disease

Crimean-Congo Hemorrhagic Fever (CCHF) is a severe tick-borne disease, endemic in many countries in Africa, the Middle East, Eastern Europe and Asia. Between 15–70% of reported cases are fatal with no approved vaccine available. In the present study, the attenuated poxvirus vector, Modified Vaccinia...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Dowall, SD, Buttigieg, KR, Findlay-Wilson, SJD, Rayner, E, Pearson, G, Miloszewska, A, Graham, VA, Carroll, MW, Hewson, R
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5049717/
https://ncbi.nlm.nih.gov/pubmed/26309231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2015.1078045
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