A Novel Vaccine against Crimean-Congo Haemorrhagic Fever Protects 100% of Animals against Lethal Challenge in a Mouse Model

Crimean-Congo Haemorrhagic Fever (CCHF) is a severe tick-borne disease, endemic in many countries in Africa, the Middle East, Eastern Europe and Asia. Between 15–70% of reported cases are fatal. There is no approved vaccine available, and preclinical protection in vivo by an experimental vaccine has...

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Autors principals: Buttigieg, Karen R., Dowall, Stuart D., Findlay-Wilson, Stephen, Miloszewska, Aleksandra, Rayner, Emma, Hewson, Roger, Carroll, Miles W.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951450/
https://ncbi.nlm.nih.gov/pubmed/24621656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091516
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