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Linking aptamer‐ligand binding and expression platform folding in riboswitches: prospects for mechanistic modeling and design

The power of riboswitches in regulation of bacterial metabolism derives from coupling of two characteristics: recognition and folding. Riboswitches contain aptamers, which function as biosensors. Upon detection of the signaling molecule, the riboswitch transduces the signal into a genetic decision....

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Bibliografiske detaljer
Udgivet i:Wiley Interdiscip Rev RNA
Main Authors: Aboul‐ela, Fareed, Huang, Wei, Abd Elrahman, Maaly, Boyapati, Vamsi, Li, Pan
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5049679/
https://ncbi.nlm.nih.gov/pubmed/26361734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.1300
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