T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo.

Organ graft rejection is a T-cell-dependent process. The activation of alloreactive T cells requires stimulation of the T-cell receptor/CD3 complex by foreign major histocompatibility complex (MHC)-encoded gene products. However, accumulating evidence suggests that, in addition to T-cell receptor oc...

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Bibliographische Detailangaben
Hauptverfasser: Turka, L A, Linsley, P S, Lin, H, Brady, W, Leiden, J M, Wei, R Q, Gibson, M L, Zheng, X G, Myrdal, S, Gordon, D
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1992
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC50492/
https://ncbi.nlm.nih.gov/pubmed/1332070
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