Molecular and Functional Analyses of the Primordial Costimulatory Molecule CD80/86 and Its Receptors CD28 and CD152 (CTLA-4) in a Teleost Fish

The moderate activation of T cells in mammals requires the costimulatory molecules, CD80 and CD86, on antigen-presenting cells to interact with their respective T cell receptors, CD28 and CD152 (CTLA-4), to promote costimulatory signals. In contrast, teleost fish (except salmonids) only possess CD80...

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Detalhes bibliográficos

Principais autores:	Tao-Zhen Lu, Xun Liu, Chang-Song Wu, Zi-You Ma, Yang Wang, Yong-An Zhang, Xu-Jie Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-06-01
coleção:	Frontiers in Immunology
Assuntos:	CD80/86 CD28 CD152 grass carp T cell activation
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.885005/full
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