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Anti-CD73 immunotherapy: A viable way to reprogram the tumor microenvironment
The ecto-5'-nucleotidase/CD73 enzyme plays a pivotal role in generating an adenosine-enriched immunosuppressed and pro-angiogenic niche supporting cancer development. The targeting of CD73 leads to reorganization of tumor microenvironment, shaping the phenotype of the infiltrating T cells. The...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Oncoimmunology |
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| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Taylor & Francis
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5048762/ https://ncbi.nlm.nih.gov/pubmed/27757316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1216292 |
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