Intra-tumoral heterogeneity in the expression of programmed-death (PD) ligands in isogeneic primary and metastatic lung cancer: Implications for immunotherapy

Purpose: There is inconclusive evidence to suggest the expression of programmed cell death (PD) ligand 1 (PD-L1) is a putative predictor of response to PD-1/PD-L1-targeted therapies in lung cancer. We evaluated the heterogeneity in the expression of PD-1 ligands in isogeneic primary and metastatic L...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncoimmunology
Egile Nagusiak: Pinato, David J., Shiner, Robert J., White, Solomon D. T., Black, James R. M., Trivedi, Pritesh, Stebbing, Justin, Sharma, Rohini, Mauri, Francesco A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2016
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048760/
https://ncbi.nlm.nih.gov/pubmed/27757309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1213934
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