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ASK1 controls spindle orientation and positioning by phosphorylating EB1 and stabilizing astral microtubules

Orientation and positioning of the mitotic spindle are involved in dictating cell division axis and cleavage site, and play important roles in cell fate determination and tissue morphogenesis. However, how spindle movement is controlled to achieve a defined alignment within the dividing cell is not...

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Опубликовано в: :Cell Discov
Главные авторы: Luo, Youguang, Ran, Jie, Xie, Songbo, Yang, Yunfan, Chen, Jie, Li, Shanshan, Shui, Wenqing, Li, Dengwen, Liu, Min, Zhou, Jun
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048754/
https://ncbi.nlm.nih.gov/pubmed/27721984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2016.33
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