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Skeletal Muscle Signal Peptide Optimization for Enhancing Propeptide or Cytokine Secretion
We have utilized hidden Markov models using HMMER software to predict and generate putative strong secretory signal peptide sequences for directing efficient secretion of cytokines from skeletal muscle for therapeutic applications. The results show that this approach can analyze signal sequences of...
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| Publicado no: | J Theor Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5048591/ https://ncbi.nlm.nih.gov/pubmed/27576355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2016.08.036 |
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