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A novel injectable BRET-based in vivo imaging probe for detecting the activity of hypoxia-inducible factor regulated by the ubiquitin-proteasome system

The ubiquitin-proteasome system (UPS) is a selective protein degradation system that plays a critical role in many essential biological processes by regulating the existence of various cellular proteins. The target proteins of UPS are recognized and tagged with polyubiquitin chains by E3 ubiquitin l...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Kuchimaru, Takahiro, Suka, Tomoya, Hirota, Keisuke, Kadonosono, Tetsuya, Kizaka-Kondoh, Shinae
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048432/
https://ncbi.nlm.nih.gov/pubmed/27698477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34311
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