Identification of a novel mechanism of blood–brain communication during peripheral inflammation via choroid plexus‐derived extracellular vesicles

Here, we identified release of extracellular vesicles (EVs) by the choroid plexus epithelium (CPE) as a new mechanism of blood–brain communication. Systemic inflammation induced an increase in EVs and associated pro‐inflammatory miRNAs, including miR‐146a and miR‐155, in the CSF. Interestingly, this...

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Pubblicato in:EMBO Mol Med
Autori principali: Balusu, Sriram, Van Wonterghem, Elien, De Rycke, Riet, Raemdonck, Koen, Stremersch, Stephan, Gevaert, Kris, Brkic, Marjana, Demeestere, Delphine, Vanhooren, Valerie, Hendrix, An, Libert, Claude, Vandenbroucke, Roosmarijn E
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048366/
https://ncbi.nlm.nih.gov/pubmed/27596437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201606271
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