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Quantitative analysis of human centrosome architecture by targeted proteomics and fluorescence imaging

Centrioles are essential for the formation of centrosomes and cilia. While numerical and/or structural centrosomes aberrations are implicated in cancer, mutations in centriolar and centrosomal proteins are genetically linked to ciliopathies, microcephaly, and dwarfism. The evolutionarily conserved m...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Bauer, Manuel, Cubizolles, Fabien, Schmidt, Alexander, Nigg, Erich A
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048348/
https://ncbi.nlm.nih.gov/pubmed/27539480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201694462
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