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RTCR: a pipeline for complete and accurate recovery of T cell repertoires from high throughput sequencing data

Motivation: High Throughput Sequencing (HTS) has enabled researchers to probe the human T cell receptor (TCR) repertoire, which consists of many rare sequences. Distinguishing between true but rare TCR sequences and variants generated by polymerase chain reaction (PCR) and sequencing errors remains...

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Bibliografiske detaljer
Udgivet i:Bioinformatics
Main Authors: Gerritsen, Bram, Pandit, Aridaman, Andeweg, Arno C., de Boer, Rob J.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048062/
https://ncbi.nlm.nih.gov/pubmed/27324198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw339
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