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Metabolomic Network Analysis of Estrogen-stimulated MCF-7 Cells – a Comparison of Over-Representation Analysis, Quantitative Enrichment Analysis and Pathway Analysis versus Metabolite Network Analysis

In the context of the Human Toxome project, mass-spectroscopy-based metabolomics characterization of estrogen-stimulated MCF-7 cells was studied in order to support the untargeted deduction of pathways of toxicity. A targeted and untargeted approach using over-representation analysis (ORA), quantita...

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Bibliografiske detaljer
Udgivet i:Arch Toxicol
Main Authors: Maertens, Alexandra, Bouhifd, Mounir, Zhao, Liang, Odwin-DaCosta, Shelly, Kleensang, Andre, Yager, James D, Hartung, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047848/
https://ncbi.nlm.nih.gov/pubmed/27039105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-016-1695-x
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