Genetic variability in a frozen batch of MCF-7 cells invisible in routine authentication affecting cell function

Common recommendations for cell line authentication, annotation and quality control fall short addressing genetic heterogeneity. Within the Human Toxome Project, we demonstrate that there can be marked cellular and phenotypic heterogeneity in a single batch of the human breast adenocarcinoma cell li...

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Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Kleensang, Andre, Vantangoli, Marguerite M., Odwin-DaCosta, Shelly, Andersen, Melvin E., Boekelheide, Kim, Bouhifd, Mounir, Fornace, Albert J., Li, Heng-Hong, Livi, Carolina B., Madnick, Samantha, Maertens, Alexandra, Rosenberg, Michael, Yager, James D., Zhaog, Liang, Hartung, Thomas
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960662/
https://ncbi.nlm.nih.gov/pubmed/27456714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28994
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